Epstein-Barr virus microRNAs in the pathogenesis of human cancers
نویسندگان
چکیده
The Epstein-Barr Virus (EBV) is a gamma-herpesvirus involved with variety of human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma. In 2004, EBV was described as one first known oncoviruses to encode viral microRNAs (miRNAs), these molecules were found interact host targets. miRNAs modulate biological processes that are critical for carcinogenesis, contributing cell transformation tumor progression EBV-associated cancers. Herein we review discuss modulators biology well their usefulness putative markers monitor onset, progression, recurrence cancers associated infection.
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ژورنال
عنوان ژورنال: Cancer Letters
سال: 2021
ISSN: ['1872-7980', '0304-3835']
DOI: https://doi.org/10.1016/j.canlet.2020.11.019